Deferred lease asset Deferred Costs, Leasing, Net, Noncurrent Entity Address, City or Town Entity Address, City or Town Employee Severance Employee Severance [Member] Operating lease commencement date Operations Commenced Date Acquisition of worldwide rights for TSHA 120 for treatment of giant axonal neuropathy. Acquisition Of Worldwide Rights For T S H A120 For Treatment Of Giant Axonal Neuropathy [Member] TSHA-120 Schedule of Reconciliation of Federal Statutory Income Tax Rate Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] Entity Ex Transition Period Entity Ex Transition Period Net Income (Loss) Available to Common Stockholders, Basic, Total Net loss Net Income (Loss) Available to Common Stockholders, Basic Earnings Per Share [Abstract] 2025 Finance Lease, Liability, to be Paid, Year Three Federal Domestic Tax Authority [Member] Issuance of common stock Stock Issued During Period, Value, New Issues Research and Development Research and Development Expense, Policy [Policy Text Block] Cash flows from financing activities Net Cash Provided by (Used in) Financing Activities [Abstract] Expected dividend yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Options granted, Aggregate Intrinsic Value Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Intrinsic Value Share based compensation arrangement by share based payment award options grants in period intrinsic value. Proceeds from term loan Proceeds From Term Loan Proceeds from term loan. Option to obtain license for GAN License For GAN [Member] License For GAN Amendment Flag Amendment Flag Forfeitures Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Cancelled In Period Share based compensation arrangement by share based payment award number of shares available for grant cancelled in period. 2025 Long-Term Debt, Maturity, Year Four Offering costs not yet paid Capital Expenditures Incurred but Not yet Paid Number of shares authorized for issuance Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Subsequent Event Type Subsequent Event Type [Domain] Schedule of Supplemental Cash Flow Information Related to Operating Leases Schedule Of Supplemental Cash Flow Information Related To Operating Leases [Table Text Block] Schedule Of Supplemental Cash Flow Information Related To Operating Leases Operating lease right-of-use assets Operating Lease, Right-of-Use Asset License and inventory purchase agreement sales related milestones payment License And Inventory Purchase Agreement Sales Related Milestones Payment License and inventory purchase agreement sales related milestones payment. Abeona Abeona Therapeutics Inc [Member] Abeona Therapeutics Inc. Debt Instrument [Table] Schedule of Long-Term Debt Instruments [Table] Less: imputed interest Less: imputed interest Lessee, Operating Lease, Liability, Undiscounted Excess Amount Assets Capitalized as Finance Leases Assets Capitalized as Finance Leases [Member] Assets capitalized as finance leases. Statement [Table] Statement [Table] Operating lease liabilities, non-current Operating lease liability, net of current portion Operating Lease, Liability, Noncurrent 2023 Finance Lease, Liability, to be Paid, Year One Lessee Disclosure [Abstract] Emerging Growth Company Emerging Growth Company Policy [Text Block] Emerging growth company. Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false] Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false] Underwriting Agreement Underwriting Agreement Member Underwriting agreement member. Operating cash flows for operating leases Operating Lease, Payments Issuance of common stock under ESPP, shares Number of shares of common stock issued under ESPP Stock Issued During Period, Shares, Employee Stock Purchase Plans Build-to-suit lease liability Build To Suit Lease Liability Build-to-suit lease liability. Preferred Stock, Shares Outstanding, Ending Balance Preferred Stock, Shares Outstanding, Beginning Balance Preferred stock, shares outstanding Preferred stock, shares outstanding Preferred Stock, Shares Outstanding Common stock reserved for future issuance Common Stock, Capital Shares Reserved for Future Issuance Auditor Firm ID Auditor Firm ID Nonvested, Weighted Average Grant Date Fair Value per Share, Beginning Balance Nonvested, Weighted Average Grant Date Fair Value per Share, Ending Balance Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Vested, Weighted Average Grant Date Fair Value per Share Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Equipment purchases and build-out of leased Facility Equipment Purchases And Build Out Of Leased Facility Equipment purchases and build-out of leased facility. Summary of Accrued Severance Activity Recorded Schedule Of Accrued Severance Activity Recorded [Table Text Block] Schedule of accrued severance activity table text block. Income Tax Authority Income Tax Authority [Domain] Deferred Tax Assets, Tax Credit Carryforwards, Total Tax credit carryforwards Deferred Tax Assets, Tax Credit Carryforwards ASU 2019-12 Accounting Standards Update 2019-12 [Member] Product and Service Product and Service [Axis] Purchase of clinical materials and reimbursement incurred development costs Purchase Of Clinical Materials And Reimbursement Incurred Development Costs Purchase of clinical materials and reimbursement incurred development costs. Share-based payment award, commencement date Share Based Compensation Arrangement By Share Based Payment Award Commencement Date Share based compensation arrangement by share based payment award commencement date. Debt Issuance Costs Debt, Policy [Policy Text Block] Cumulative Effect, Period of Adoption, Adjustment Cumulative Effect, Period of Adoption, Adjustment [Member] Construction in progress Construction in Progress, Gross Employee-related Liabilities, Current, Total Accrued compensation Employee-related Liabilities, Current Leases Lessee, Operating Leases [Text Block] Stock Options Stock Options Share-Based Payment Arrangement, Option [Member] Weighted average remaining lease term (in years) - Operating leases Operating Lease, Weighted Average Remaining Lease Term Total liabilities and stockholders' equity Liabilities and Equity Right-of-use assets Right-of-use assets Deferred Tax Liabilities, Leasing Arrangements Plan Name Plan Name [Domain] Percentage of headcount reduced Restructuring and Related Cost, Number of Positions Eliminated, Period Percent Change in Accounting Principle, Accounting Standards Update, Adopted [true false] Change in Accounting Principle, Accounting Standards Update, Adopted [true false] Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Income Statement [Abstract] Outside the United States Non-US [Member] Share-based Payment Arrangement, Tranche Three Share-Based Payment Arrangement, Tranche Three [Member] Organization and Description of Business Operations Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Proceeds from common stock issuances under ESPP Proceeds from Stock Plans Weighted average remaining lease term (in years) - Finance leases Finance Lease, Weighted Average Remaining Lease Term Deferred revenue Deferred Revenue Deferred Revenue, Total Finance lease liabilities, current Finance Lease, Liability, Current Sale of Stock Sale of Stock [Domain] Total current liabilities Liabilities, Current Issuance of common stock under ESPP Stock Issued During Period, Value, Employee Stock Purchase Plan Operating Loss Carryforwards, Total Net operating loss carryforward Operating Loss Carryforwards 2025 Lessee, Operating Lease, Liability, to be Paid, Year Three 2026 Long-Term Debt, Maturity, Year Five 2023 Operating Leases, Future Minimum Payments Due, Next 12 Months Interest Expense, Total Interest expense Interest Expense Share-based Payment Arrangement, Tranche Two Share-Based Payment Arrangement, Tranche Two [Member] Organization And Description Of Business Operations [Table] Organization And Description Of Business Operations [Table] Organization and description of business operations. Income Taxes Income Tax, Policy [Policy Text Block] Deferred revenue Increase (Decrease) in Contract with Customer, Liability Percentage of common stock price purchased through payroll deductions Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate Convertible preferred stock, shares authorized Preferred stock, shares authorized Preferred Stock, Shares Authorized Total deferred tax liabilities Total deferred tax liabilities Deferred tax liabilities Deferred Tax Liabilities, Net Shelf Registration,term Shelf Registration Term Shelf registration,term Upfront payment period Upfront Payment Period Upfront payment period. Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Cumulative Effect, Period of Adoption [Axis] Weighted average discount rate - Operating leases Operating Lease, Weighted Average Discount Rate, Percent Variable Rate Variable Rate [Axis] Entity Small Business Entity Small Business Collaborative Arrangement and Arrangement Other than Collaborative Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Stock-Based Compensation Compensation Related Costs, Policy [Policy Text Block] Increase (Decrease) in Due to Related Parties, Total Due to related party Increase (Decrease) in Due to Related Parties Restructuring and Related Activities [Abstract] Prepaid clinical trial Prepaid Clinical Trial Prepaid clinical trial. Total current assets Assets, Current Property, Plant and Equipment [Line Items] Property, Plant and Equipment [Line Items] Accumulated Deficit Cumulative Earnings (Deficit) Weighted average common shares outstanding, basic Weighted Average Number of Shares Outstanding, Basic Weighted Average Number of Shares Outstanding, Basic, Total Risks and Uncertainties Risks And Uncertainties Policy [Text Block] Risks and uncertainties. Total lease liabilities Total lease liabilities Finance Lease, Liability City Area Code City Area Code Outstanding, Aggregate Intrinsic Value, Beginning Balance Outstanding, Aggregate Intrinsic Value, Ending Balance Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Option award, canceled Options cancelled or forfeited, Stock Options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Share-Based Payment Arrangement [Abstract] Exit and Disposal Activities Exit And Disposal Activities [Member] Exit and disposal activities. Tax Cuts and Jobs Act, adjusted taxable income limitation percentage Tax Cuts And Jobs Act Adjusted Taxable Income Limitation Percentage Tax cuts and jobs act adjusted taxable income limitation percentage. Total liabilities Liabilities Private Placement Private Placement [Member] Document Period End Date Document Period End Date Unvested RSAs Restricted Stock Awards Restricted Stock [Member] Construction in Progress Construction in Progress [Member] Share-based payment award, options, weighted-average grant date fair value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Operating lease extend term of contract Lessee, Operating Lease, Renewal Term Percentage of prepayment of facility Percentage Of Prepayment Of Facility Percentage of prepayment of facility. Share-based Payment Arrangement, Tranche One Share-Based Payment Arrangement, Tranche One [Member] Statistical Measurement Statistical Measurement [Axis] Durham Lease Durham Lease [Member] Durham lease. Other Other Assets, Current Subsequent Event [Line Items] Subsequent Event [Line Items] Number of shares awarded Replacement restricted units granted, Number of Shares Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Replacement Units Grants In Period Share based compensation arrangement by share based payment award equity instruments other than options replacement units grants in period. Cancelled Options Cancelled Options [Member] Cancelled options. Total assets Assets ASU 2016-02 Accounting Standards Update 2016-02 [Member] State State and Local Jurisdiction [Member] 2026 Operating Leases, Future Minimum Payments, Due in Four Years Long-term Debt, Excluding Current Maturities, Total Term loan, net Long-Term Debt, Excluding Current Maturities Net loss per common share, diluted Earnings Per Share, Diluted Earnings Per Share, Diluted, Total Build-to-Suit Lease Build-to-Suit Lease Build To Suit Lease Policy [Text Block] Build-to-suit lease. Schedule of Common Stock Equivalents Outstanding Excluded from Computation of Diluted Net Loss Per Share Attributable to Common Stockholders Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Exit fee recorded as debt discount Debt Instrument, Unamortized Discount, Noncurrent Entity Address, Postal Zip Code Entity Address, Postal Zip Code Document Fiscal Period Focus Document Fiscal Period Focus Tax credit carryforward expiration or due date year Tax Credit Carryforward Expiration Or Due Date Year Tax credit carryforward expiration or due date year. Restricted Cash, Total Restricted cash Restricted Cash Deferred offering costs Deferred Offering Costs Deferred Tax Assets, Valuation Allowance, Total Valuation allowance Deferred Tax Assets, Valuation Allowance Preferred stock, $0.00001 par value per share; 10,000,000 shares authorized and no shares issued and outstanding as of December 31, 2022 and December 31, 2021 Preferred Stock, Value, Issued, Ending Balance Preferred Stock, Value, Issued, Beginning Balance Preferred Stock, Value, Issued, Total Preferred Stock, Value, Issued APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total Stock-based compensation APIC, Share-Based Payment Arrangement, Increase for Cost Recognition 2027 Finance Lease, Liability, to be Paid, Year Five Other Other Payments for (Proceeds from) Other Investing Activities Counterparty Name Counterparty Name [Domain] Total lease liabilities Total lease liabilities Operating Lease, Liability Net cash provided by financing activities Net Cash Provided by (Used in) Financing Activities Total Lease Commitments Operating Leases, Future Minimum Payments Due Fixed assets Fixed assets Deferred Tax Liabilities, Property, Plant and Equipment Statement of Financial Position [Abstract] Entity File Number Securities Act File Number Organization and Description of Business Operations [Line Items] Organization And Description Of Business Operations [Line Items] Organization and description of business operations. Total lease payments Finance Lease, Liability, to be Paid Impairment Charge On Construction In Progress And Finance Lease Right Of Use Asset Impairment charges to construction in process and finance lease right of use assets Construction In Progress And Finance Lease Right Of Use Asset Queens Agreement Queens Agreement [Member] Queen's agreement. Statement of Cash Flows [Abstract] Balance Sheet Related Disclosures [Abstract] Grants Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Granted In Period Share based compensation arrangement by share based payment award number of shares available for grant granted in period.. Thereafter Lessee, Operating Lease, Liability, to be Paid, after Year Five Sales Agents Sales Agent [Member] Sales agent. Income Tax Disclosure [Table] Income Tax Disclosure [Table] Income tax disclosure. Retirement Plan Retirement Benefits [Text Block] Preclinical activities period under sponsored research agreements Preclinical Activities Period Under Sponsored Research Agreements Preclinical activities period under sponsored research agreements. Geographical Geographical [Domain] Statistical Measurement Statistical Measurement [Domain] Statement of Stockholders' Equity [Abstract] Sale of Stock Sale of Stock [Axis] Share-based payment award, plan modification, incremental cost Share-Based Payment Arrangement, Plan Modification, Incremental Cost Auditor Location Auditor Location Schedule of Lease Cost Lease, Cost [Table Text Block] Subsequent Events [Abstract] Options expired, Weighted Average Exercise Price Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price Weighted Average Remaining Contractual Life, Options exercisable at December 31, 2021 Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Proceeds from issuance of common stock to Astellas, net of offering costs Net proceeds from issuance of common stock Proceeds from Issuance of Common Stock Long-term Debt, Type Long-Term Debt, Type [Axis] Percentage of gross sales price per share of common stock Percentage Of Sale Price Per Share Of Common Stock Percentage of sale price per share of common stock. Schedule of Property, Plant and Equipment Property, Plant and Equipment [Table Text Block] Summary of Allocation for Transaction Price to the Three Performance Obligations Summary Of Transaction Price Allocation [Table Text Block] Summary Of Transaction Price Allocation Other Proceeds from (Payments for) Other Financing Activities Concentrations of Credit Risk Concentration Risk, Credit Risk, Policy [Policy Text Block] Accounting Standards Update [Extensible Enumeration] Antidilutive Securities Antidilutive Securities [Axis] Maximum borrowing capacity Line of Credit Facility, Maximum Borrowing Capacity Preferred stock, par value per share Preferred Stock, Par or Stated Value Per Share Sale-related milestones per licensed product and royalties on net sales of licensed products payable Sale Related Milestones Per Licensed Product And Royalties On Net Sales Of Licensed Products Payable Sale-related milestones per licensed product and royalties on net sales of licensed products payable. Lessee, Lease, Description [Line Items] Supplemental Financial Information Supplemental Balance Sheet Disclosures [Text Block] Subsequent Events Subsequent Events [Text Block] Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Weighted average common shares outstanding, diluted Weighted Average Number of Shares Outstanding, Diluted Weighted Average Number of Shares Outstanding, Diluted, Total Significant Accounting Policies [Table] Significant Accounting Policies [Table] Significant accounting policies table. Share-based payment award, unvested RSU/RSA granted, compensation cost not yet recognized Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount January 1, 2022 until September 30, 2022 Term Loan From January One Twenty Twenty Two Until September Thirty Twenty Twenty Two [Member] Term loan from january one twenty twenty two until september thirty twenty twenty two. Computer Equipment Computer Equipment [Member] General and Administrative Expense General and Administrative Expense [Member] Share-based payment award, options, compensation cost not yet recognized Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Strategic Reprioritization Business Acquisition, Integration, Restructuring and Other Related Costs [Text Block] Current Fiscal Year End Date Current Fiscal Year End Date Change in fair value of preferred stock tranche liability Non cash expenses due to remeasured fair value of tranche liability Change in fair value of preferred stock tranche liability Change In Fair Value Of Preferred Stock Tranche Liability Change in fair value preferred stock tranche liability. Depreciation, Total Depreciation expense Depreciation Through August 13, 2023 Term Loan Through August Thirteen Twenty Twenty Three [Member] Term loan through august thirteen twenty twenty three. Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total Cash, cash equivalents and restricted cash at the beginning of the period Cash, cash equivalents and restricted cash at the end of the period Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations Payroll and Payroll Related Costs Payroll And Payroll Related Costs [Member] Payroll and payroll-related costs. Other Assets, Noncurrent, Total Other non-current assets Other Assets, Noncurrent Entity Address, Address Line One Entity Address, Address Line One Offering to Astellas Offering to Astellas [Member] Offering to Astellas. Document Annual Report Document Annual Report Supplemental disclosure of cash flow information: Supplemental Cash Flow Information [Abstract] Components of Deferred Tax Assets [Abstract] Income Tax Expense (Benefit), Total Provision for income taxes Income Tax Expense (Benefit) Research and development tax credits Effective Income Tax Rate Reconciliation, Nondeductible Expense, Research and Development, Percent Convertible Preferred Stock Convertible Preferred Stock Policy [Text Block] Convertible preferred stock. October 1, 2022 until March 31, 2023 Term Loan From October One Twenty Twenty Two Until March Thirty One Twenty Twenty Three [Member] Term loan from october one twenty twenty two until march thirty one twenty twenty three. Finance Lease Finance Lease, Liability, to be Paid [Abstract] Income Taxes Income Tax Disclosure [Text Block] Vesting Vesting [Axis] Preferred Stock, Shares Issued, Total Preferred stock, shares issued Preferred stock, shares issued Preferred Stock, Shares Issued Other Other Accrued Liabilities, Current Payments to Acquire Property, Plant, and Equipment, Total Purchase of property, plant and equipment Payments to Acquire Property, Plant, and Equipment Income Tax Disclosure [Abstract] Option to purchase additional number of shares Option To Purchase Additional Number Of Shares Option to purchase additional number of shares. Change in Accounting Principle, Accounting Standards Update, Adoption Date Change in Accounting Principle, Accounting Standards Update, Adoption Date Significant Accounting Policies [Line Items] Significant Accounting Policies [Line Items] Significant accounting policies line items. Transaction Price Allocation Transaction price Transaction Price Transaction price. Number of shares issued or sell Issuance of common stock, shares Number of shares issued Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Total Accruals and reserves Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals Laboratory Equipment Laboratory Equipment [Member] Laboratory equipment. Replacement restricted units granted, Weighted Average Grant Date Fair Value per Share Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Replacement Units Grants In Period Weighted Average Grant Date Fair Value Share based compensation arrangement by share based payment award equity instruments other than options replacement units grants in period weighted average grant date fair value. Additional milestone payments Additional Milestone Payments Additional Milestone payments. Property, plant and equipment in accounts payable and accrued expenses Property And Equipment In Accounts Payable And Accrued Expenses Property and equipment in accounts payable and accrued expenses. Plan adjustments and amendments Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Plan Adjustments And Amendments In Period Share based compensation arrangement by share based payment award number of shares available for grant plan adjustments and amendments in period. Auditor Name Auditor Name 2026 Finance Lease, Liability, to be Paid, Year Four Schedule of Aggregate Lease Commitments Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block] Options cancelled or forfeited, Weighted Average Exercise Price Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Loss from operations Operating Income (Loss) Percentage of interest rate Debt Instrument, Interest Rate, Stated Percentage Lease, option to extend description Lessee, Operating Lease, Option to Extend Share-based payment award, terms of award issuance Share-Based Compensation Arrangement by Share-Based Payment Award, Terms of Award Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Probability of option exercise Probability Of An Option Exercise Probability of Option Exercise Award requisite service vesting period Share-Based Compensation Arrangement by Share-Based Payment Award, Award Requisite Service Period Dallas Lease Amendment Dallas Lease Amendment [Member] Dallas lease amendment. Research and development license expense Research and Development in Process Accrued professional and consulting fees Accrued Professional Fees, Current Total accrued expenses and other current liabilities Accrued expenses and other current liabilities Accrued Liabilities and Other Liabilities Entity Filer Category Entity Filer Category Severance paid Severance and termination-related costs Severance Costs Restructuring Plan [Domain] Minimum licensed product to develop obtain regulatory approval for and commercialize Minimum Licensed Product To Develop Obtain Regulatory Approval For And Commercialize Minimum licensed product to develop obtain regulatory approval for and commercialize. Total operating expenses Operating Expenses Purchase of research and development license Payments to Acquire in Process Research and Development Entity Current Reporting Status Entity Current Reporting Status Proceeds from Term Loan, net Proceeds From Term Loan Net Proceeds from term loan, net. ICFR Auditor Attestation Flag ICFR Auditor Attestation Flag Options exercisable at December 31, 2021, Aggregate Intrinsic Value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Prime Rate Prime Rate [Member] Non-cash impairment charge Asset Impairment Charges Asset Impairment Charges, Total Accrued license fees Accrued License Fees Current Accrued license fees current. Total stockholders’ equity Balance Balance Stockholders' Equity Attributable to Parent Percentage of fully diluted common stock shares outstanding Percentage Of Fully Diluted Common Stock Shares Outstanding Percentage of fully diluted common stock shares outstanding. Certain Employees and Consultants Certain Employees And Consultants [Member] Certain employees and consultants. Acquisition of property, plant and equipment funded by landlord Noncash or Part Noncash Acquisition, Fixed Assets Acquired Documents Incorporated by Reference Documents Incorporated by Reference [Text Block] Entity Tax Identification Number Entity Tax Identification Number Income Statement Location Income Statement Location [Axis] Cancelled or forfeited, Number of Shares Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Common stock, $0.00001 par value per share; 200,000,000 shares authorized and 63,207,507 and 38,473,945 issued and outstanding as of December 31, 2022 and December 31, 2021 respectively Common Stock, Value, Issued, Ending Balance Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Total Common Stock, Value, Issued Retained Earnings (Accumulated Deficit), Ending Balance Retained Earnings (Accumulated Deficit), Beginning Balance Retained Earnings (Accumulated Deficit), Total Accumulated deficit Accumulated deficit Retained Earnings (Accumulated Deficit) Cumulative Effect, Period of Adoption [Domain] Equity Components Equity Components [Axis] Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Total Non-qualified stock options Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits License agreement commercial milestones payment License Agreement Commercial Milestones Payment License agreement commercial milestones payment. Maximum construction allowance provided by landlord per rentable square foot Maximum Construction Allowance Provided By Landlord Per Rentable Square Foot Maximum construction allowance provided by landlord per rentable square foot. Accounting Standards Update Accounting Standards Update [Domain] Cash and Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Leases [Abstract] Schedule of Prepaid Expenses and Other Current Assets Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block] Payment of one-time upfront license fee Payment Of One Time Upfront License Fee Payment of one-time upfront license fee. Entity Emerging Growth Company Entity Emerging Growth Company Payment of sales commissions and other offering costs Payment Of Sales Commissions And Other Offering Costs Payment of sales commissions and other offering costs. Operating expenses: Operating Expenses [Abstract] Options exercisable at December 31, 2022 Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number Revenue Recognition Revenue [Policy Text Block] Research and experimentation expenditures amortized period Research and Experimentation Expenditures Amortized Period Research and experimentation expenditures amortized period. Expected term in years Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Upfront payment Upfront Payment Upfront payment. Operating Lease Lessee, Operating Lease, Liability, to be Paid [Abstract] Entity Voluntary Filers Entity Voluntary Filers Retirement Benefits [Abstract] Document Transition Report Document Transition Report Thereafter Operating Leases, Future Minimum Payments, Due Thereafter 2024 Long-Term Debt, Maturity, Year Three Share-based payment award, RSU/RSA granted, weighted average grant date fair value Restricted units/stock granted, Weighted Average Grant Date Fair Value per Share Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Total other expense, net Nonoperating Income (Expense) Impairment of long-lived assets Impairment, Long-Lived Asset, Held-for-Use, Total Impairment losses Impairment, Long-Lived Asset, Held-for-Use Net operating loss carryforward percentage Net Operating Loss Carryforward Percentage Net operating loss carryforward percentage. Astellas Agreements Research, Collaboration, Grant and License Agreements Collaborative Arrangement Disclosure [Text Block] Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Maximum number of shares employees may purchase during offering period Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Number of Shares Per Employee Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Regulatory related milestones obligation payable Regulatory Related Milestones Obligation Payable Regulatory related milestones obligation payable. Payment of shelf registration costs Payment Of Shelf Registration Costs Payment of shelf registration costs. Net loss Net loss Net Income (Loss) Attributable to Parent Lease liabilities, current portion Operating lease liabilities, current Operating Lease, Liability, Current R&E expenditures Deferred Tax Assets, in Process Research and Development Rett research and development activities Abeona Rett agreement. Abeona Rett Agreement [Member] Abeona Rett Agreement Additional Paid-in Capital Additional Paid-in Capital [Member] Collaborative Arrangement and Arrangement Other than Collaborative Collaborative Arrangement and Arrangement Other than Collaborative [Domain] New Plan Two Thousand Twenty Stock Incentive Plan [Member] Two thousand twenty stock incentive plan. Deferred Tax Assets, Operating Loss Carryforwards, Total Net operating loss carryforwards Deferred Tax Assets, Operating Loss Carryforwards Schedule of Restricted Stock Units Activity Schedule of Nonvested Restricted Stock Units Activity [Table Text Block] Debt instrument, maturity end date Debt Instrument, Maturity Date Range, End Schedule of Future Principal Debt Payments on Term Loan Agreement Schedule of Maturities of Long-Term Debt [Table Text Block] Common stock shares issued and sold Common Stock Shares Issued And Sold Common stock shares issued and sold. Restructuring Plan [Axis] Entity Registrant Name Entity Registrant Name Option to obtain license for Rett License For RETT [Member] License For RETT Cash and Cash Equivalents, at Carrying Value, Ending Balance Cash and Cash Equivalents, at Carrying Value, Beginning Balance Cash and Cash Equivalents, at Carrying Value, Total Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Net Loss Per Common Share Earnings Per Share [Text Block] Schedule of Assumptions Used to Estimate Fair Value of Stock Options Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Debt instrument, maturity date Debt Instrument, Maturity Date Lessee, Lease, Description [Table] Revenues Revenues Revenues, Total Share-based Payment Arrangement, Noncash Expense, Total Stock-based compensation Share-Based Payment Arrangement, Noncash Expense Property, Plant and Equipment, Net, Ending Balance Property, Plant and Equipment, Net, Beginning Balance Property, plant and equipment, net Property, plant and equipment, net Property, Plant and Equipment, Net Debt Instrument, Unamortized Discount, Total Unamortized debt discount Debt Instrument, Unamortized Discount Award Type Award Type [Domain] Statement [Line Items] Statement [Line Items] Percentage of payroll deductions of employee's compensation during offering period Share-Based Compensation Arrangement by Share-Based Payment Award, Discount from Market Price, Offering Date Issuance of common stock, upon vesting and settlement of restricted stock units Issuance Of Common Stock Upon Vesting And Settlement Of Restricted Stock Units Value Issuance of common stock upon vesting and settlement of restricted stock units value. Title of 12(b) Security Title of 12(b) Security Increase (Decrease) in Accounts Payable, Total Accounts payable Increase (Decrease) in Accounts Payable Restructuring Cost and Reserve [Line Items] Common Stock Common Stock [Member] Share-based payment award, expiration period Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Restricted Cash Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block] Income Tax Disclosure [Line Items] Income Tax Disclosure [Line Items] Income tax disclosure. Cash flows from operating activities Net Cash Provided by (Used in) Operating Activities [Abstract] Equity Component Equity Component [Domain] Less: imputed interest Less: imputed interest Finance Lease, Liability, Undiscounted Excess Amount Entity Address, State or Province Entity Address, State or Province 2026 Lessee, Operating Lease, Liability, to be Paid, Year Four Geographical Geographical [Axis] Warrants associated with loan facility Warrants and Rights Outstanding Existing Plan 2020 Equity Incentive Plan Two Thousand Twenty Equity Incentive Plan [Member] Two thousand twenty equity incentive plan. Net decrease in cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Document Type Document Type Cash paid for interest Interest Paid, Excluding Capitalized Interest, Operating Activities Build-to-suit lease liability Lease Obligation Incurred United States UNITED STATES Entity Shell Company Entity Shell Company License fee payment Payment Of License Fee Payment of license fee. Stock-based compensation expense Share-Based Payment Arrangement, Expense Fair Value of Financial Instruments Fair Value of Financial Instruments, Policy [Policy Text Block] Interest Expense, Long-term Debt, Total Interest expense related to term loan Interest Expense, Long-Term Debt Derecognized build to suit lease liablility Derecognized Build To Suit Lease Liability Derecognized Build To Suit Lease Liability Sales Agreement Sales Agreement [Member] Sales Agreement. Other permanent differences Effective Income Tax Rate Reconciliation Other Permanent Differences Effective income tax rate reconciliation other permanent differences. Security Exchange Name Security Exchange Name Term Loan Term Loan Facility [Member] Term loan facility. Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Share-based Payment Arrangement, Tranche Four Share Based Compensation Award Tranche Four [Member] Share based compensation award tranche four. Finance lease liabilities, non-current Finance, lease liabilities, non-current Finance Lease, Liability, Noncurrent Cash Flow, Operating Activities, Lessee [Abstract] Significant Accounting Policies Significant Accounting Policies [Text Block] Net cash used in operating activities Net Cash Provided by (Used in) Operating Activities Share-based payment award, compensation cost not yet recognized, weighted-average period of recognition Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Outstanding, Weighted Average Remaining Contractual Life Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Commitments and Contingencies Disclosure [Abstract] Accrued severance balance Accrued severance recorded Accrued Severance Balance Accrued severance balance. Operating lease cost Operating Lease, Cost Accrued clinical trial Accrued Clinical Trial Current Accrued clinical trial current. Schedule of Accrued Expenses and Other Current Labilities Schedule Of Accrued Expense And Other Current Labilities Table [Text Block] Schedule of accrued expense and other current labilities. Unvested RSUs Restricted Stock Units Restricted Stock Units (RSUs) [Member] Schedule of Aggregate Lease Commitments Lessee, Operating Lease, Liability, Maturity [Table Text Block] Principles of Consolidation Consolidation, Policy [Policy Text Block] 2024 Finance Lease, Liability, to be Paid, Year Two Through August 13, 2022 Term Loan Through August Thirteen Twenty Twenty Two [Member] Term loan through august thirteen twenty twenty two. Change in valuation allowance Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent Recently Adopted Accounting Pronouncements New Accounting Pronouncements, Policy [Policy Text Block] Amount required to place in escrow account Escrow Deposit Common stock, shares outstanding Balance, shares Balance, shares Common Stock, Shares, Outstanding Loan with Silicon Valley Bank Debt Disclosure [Text Block] Deferred revenue Deferred Revenue, Current Deferred Revenue, Current, Total Cash flows from investing activities Net Cash Provided by (Used in) Investing Activities [Abstract] Derecognized build to suite lease asset Derecognized Build To Suit Lease Asset Presented In Property Plant Equipment Derecognized Build To Suit Lease Asset Presented In Property Plant Equipment Accrued severance Accrued Severance Accrued Severance Commitments and contingencies - Note 11 Commitments and Contingencies Schedule of Supplemental Information Related to Remaining Lease Term and Discount Rate Schedule Of Supplemental Information Related To Remaining Lease Term And Discount Rate [Table Text Block] Schedule of supplemental information related to remaining lease term and discount rate. Common Stock, Shares, Issued, Total Common stock, shares issued Common Stock, Shares, Issued License and inventory purchase agreement regulatory related milestones payment License And Inventory Purchase Agreement Regulatory Related Milestones Payment License and inventory purchase agreement regulatory related milestones payment. Variable Rate Variable Rate [Domain] Minimum Minimum [Member] Minimum [Member] Underwriter agreed to purchase share price of per share Underwriter Agreed To Purchase Share Price Of Per Share Underwriter agreed to purchase share price of per share. Issuance of common stock, upon vesting and settlement of restricted stock units, shares Issuance Of Common Stock Upon Vesting And Settlement Of Restricted Stock Unit Shares Issuance of common stock upon vesting and settlement of restricted stock unit shares. Securities Purchase Agreement Securities Purchase Agreement Member Securities purchase agreement member. Build-to-suit lease liability Built To Suit Lease Liability Built-to-suit lease liability. Leases Lessee, Leases [Policy Text Block] Options exercisable at December 31, 2021, Weighted Average Exercise Price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Accounting Standards Update Accounting Standards Update [Axis] Public Offering Public Offering [Member] Public Offering [Member] Debt Instrument Debt Instrument [Axis] Astellas Astellas [Member] Astellas [Member] Stockholders' equity Stockholders' Equity Attributable to Parent [Abstract] State tax Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent Counterparty Name Counterparty Name [Axis] Entity Address Address Line2 Entity Address, Address Line Two Debt instrument, maturity start date Debt Instrument, Maturity Date Range, Start Cancelled or forfeited, Weighted Average Grant Date Fair Value per Share Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Accrued expenses and other liabilities Increase Decrease In Accrued Expense And Other Liabilities Increase decrease in accrued expense and other liabilities. Deferred rent liabiilities and tenant improvement allowances Deferred Rent Liabiilities And Tenant Improvement Allowances Deferred Rent Liabiilities And Tenant Improvement Allowances Award Type Award Type [Axis] Other Noncash Income (Expense), Total Other Other Noncash Income (Expense) Subsequent Event Subsequent Event [Member] Build-to-Suit Lease Build To Suit Lease [Member] Build-to-suit lease. Total deferred tax assets Deferred Tax Assets, Gross Impairment of Long-Lived Assets Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block] License Agreement for CLN7 License Agreement For C L N7 [Member] License agreement for CLN7. Gross proceeds of Private Placement Aggregate gross proceeds Proceeds from Issuance of Private Placement 2022 Operating Leases, Future Minimum Payments, Remainder of Fiscal Year Other income (expense): Nonoperating Income (Expense) [Abstract] Research and Development Expense, Total Research and development Research and Development Expense Future minimum remianing lease payments Total lease payments Lessee, Operating Lease, Liability, to be Paid Restructuring Type [Axis] Operating lease term of contract Lessee, Operating Lease, Term of Contract Difference of market value paid Difference Of Market Value Paid Difference of market value paid Pegasus Park L L C Pegasus Park L L C [Member] Pegasus Park, LLC. Intangibles Deferred Tax Assets, Goodwill and Intangible Assets Entity Central Index Key Entity Central Index Key Valuation allowance increased Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount 2024 Operating Leases, Future Minimum Payments, Due in Two Years Right-of-use assets obtained in exchange for lease liabilities Right-of-Use Asset Obtained in Exchange for Finance Lease Liability Accounting Policies [Abstract] Share-based payment award, expiration date Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Date Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total Accumulated depreciation Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Schedule Of Property Plant And Equipment [Table] Property, Plant and Equipment [Table] Expected volatility Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis] Weighted average discount rate - Finance leases Finance Lease, Weighted Average Discount Rate, Percent Long-lived assets Long-Lived Assets Regulatory milestone fee paid Regulatory Milestone Fee Paid Regulatory milestone fee paid. Available for grant end of period Available for grant beginning of period Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Stock-Based Compensation Share-Based Payment Arrangement [Text Block] Prepaid insurance Prepaid Insurance Subsequent Event [Table] Subsequent Event [Table] General and Administrative Expense, Total General and administrative General and Administrative Expense Accrued property, plant, and equipment Accrued Property Plant And Equipment Current Accrued property, plant, and equipment current. Organization, Consolidation and Presentation of Financial Statements [Abstract] Outstanding, Weighted Average Exercise Price, Beginning balance Outstanding, Weighted Average Exercise Price, Ending balance Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price RA Session II President And Chief Executive Officer [Member] President and chief executive officer. Percentage of automatic increase every year in common stock shares reserved for future issuance Percentage Of Automatic Increase Every Year In Common Stock Shares Reserved For Future Issuance Percentage of automatic increase every year in common stock shares reserved for future issuance. Research and Development Expense Research and Development Expense [Member] License agreement sales-related milestones maximum amount payable License Agreement Sales Related Milestones Maximum Amount Payable License agreement sales-related milestones maximum amount payable. Number of operating lease landlord square feet manufacturing facility Property Subject to or Available for Operating Lease, Number of Units Total lease cost Lease, Cost Adjustments to reconcile net loss to net cash used in operating activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Accumulated Deficit Retained Earnings [Member] Employee Stock Purchase Plan (ESPP) Employee Stock Purchase Plans [Member] Employee stock purchase plans. Income tax provision (benefit) Effective Income Tax Rate Reconciliation, Percent Research Collaboration And License Agreements [Abstract] Research, collaboration and license agreements. Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Number of distinct and active clinical stage Number Of Distinct And Active Clinical Stage Number of distinct and active clinical stage. At-the-Market Offering At The Market Offering [Member] At the market offering. Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration] Property, Plant and Equipment, Gross, Ending Balance Property, Plant and Equipment, Gross, Beginning Balance Property, Plant and Equipment, Gross, Total Property and equipment, gross Property, Plant and Equipment, Gross Recently Issued Accounting Pronouncements Recently Issued Accounting Pronouncements Policy Policy [Text Block] Recently issued accounting pronouncements policy. Share-based payment award, vesting rights percentage Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage Additional Paid in Capital, Ending Balance Additional Paid in Capital, Beginning Balance Additional Paid in Capital, Total Additional paid-in capital Additional Paid in Capital Entity Interactive Data Current Entity Interactive Data Current Term of contract, not yet commenced Lessee, Operating Lease, Lease Not yet Commenced, Term of Contract Entity Public Float Entity Public Float Schedule of Stock Option Activity Share-Based Payment Arrangement, Activity [Table Text Block] 2023 Lessee, Operating Lease, Liability, to be Paid, Year One Clinical, regulatory and commercial milestones to be received Clinical Regulatory And Commercial Milestones To Be Received Clinical, regulatory and commercial milestones to be received. Leasehold Improvements Leasehold Improvements [Member] License agreement regulatory milestones payment License Agreement Regulatory Milestones Payment License agreement regulatory milestones payment. Offering costs Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs April 1, 2023 until December 31, 2023 Term Loan From April One Twenty Twenty Three Until December Thirty One Twenty Twenty Three [Member] Term loan from april one twenty twenty three until december thirty one twenty twenty three. Percentage of annual default interest rate Percentage Of Annual Default Interest Rate Percentage of annual default interest rate. Share-based payment award, options grant date fair value Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Grant Date Fair Value Share based compensation arrangement by share based payment award options grants in period grant date fair value. Local Phone Number Local Phone Number Statutory rate Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Schedule of Calculation of Basic and Diluted Net Loss Per Common Share Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Schedule of Share Based Compensation Available for Grant under Incentive Plans Schedule Of Share Based Compensation Available For Grant [Table Text Block] Schedule of share based compensation available for grant. Award vesting period Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Debt Disclosure [Abstract] Excise tax rate on corporate buy-backs Excise Tax Rate Percentage Excise tax rate percentage. Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Unrecognized tax benefits to change significantly over next 12 months Significant Change in Unrecognized Tax Benefits is Reasonably Possible, Amount of Unrecorded Benefit Options granted for purchase an aggregate share of common stock Share-based payment award, options granted Options granted, Stock Options Unrecognized Tax Benefits, Period Increase (Decrease), Total Increase in the amount of gross unrecognized tax benefits Unrecognized Tax Benefits, Period Increase (Decrease) Other Liabilities, Noncurrent, Total Other non-current liabilities Other Liabilities, Noncurrent Income Statement Location Income Statement Location [Domain] Options expired, Stock Options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expirations in Period Purchase of research and development license not yet paid Research And Development License Not Yet Paid Research and development license not yet paid. Other Deferred Tax Assets, Tax Deferred Expense, Other Aggregate offering price from sale of common stock Aggregate Offering Price From Sale Of Common Stock Aggregate offering price from sale of common stock. Nonvested, Number of Shares, Beginning Balance Nonvested, Number of Shares, Ending Balance Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Schedule of Future Minimum Commitments Under Company's Operating and Finance Leases Lessee, Operating And Finance Lease, Liability, Maturity [Table Text Block] Lessee, operating and finance lease, liability, maturity . Term Loan, net Long-Term Debt Increase (Decrease) in Prepaid Expense and Other Assets, Total Prepaid expenses and other assets Increase (Decrease) in Prepaid Expense and Other Assets Lease liabilities Deferred Tax Assets Lease Liabilities Deferred tax assets lease liabilities. Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Date of incorporation Entity Incorporation, Date of Incorporation Outstanding. Stock Options, Beginning Balance Outstanding. Stock Options, Ending Balance Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Share price Preferred stock, issuing price per share Share Price Debt Instrument, Name Debt Instrument, Name [Domain] Document Fiscal Year Focus Document Fiscal Year Focus 2024 Lessee, Operating Lease, Liability, to be Paid, Year Two Accrued research and development Accrued Research And Development Current Accrued research and development current. Vesting Vesting [Domain] Net loss per common share, basic Earnings Per Share, Basic Earnings Per Share, Basic, Total Fair value of shares transferred, Value Fair Value Of Shares Transferred Value Fair value of shares transferred value. ASSETS Assets [Abstract] Net deferred taxes Deferred Tax Assets, Net Deferred rent liabilities Deferred Rent Liabiilities Deferred Rent Liabiilities Total prepaid expenses and other current assets Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Interest income Interest Income (Expense), Nonoperating, Net Long-Lived Tangible Asset Long-Lived Tangible Asset [Axis] Schedule of Restructuring and Related Costs [Table] LIABILITIES AND STOCKHOLDERS' EQUITY Liabilities and Equity [Abstract] Property Plant and Equipment, net Property, Plant and Equipment, Policy [Policy Text Block] Antidilutive Securities, Name Antidilutive Securities, Name [Domain] Income Tax Authority Income Tax Authority [Axis] Type of Restructuring [Domain] Schedule of Restricted Stock Awards Activity Nonvested Restricted Stock Shares Activity [Table Text Block] Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total Net loss Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Current assets: Assets, Current [Abstract] Schedule of Significant Components of Net Deferred Tax Asset Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Gross proceeds including upfront payments Proceeds From Issuance Of Common Stock Including Upfront Payments Proceeds from issuance of common stock including upfront payments. Finance Lease, Liability, Statement of Financial Position [Extensible Enumeration] Contribution to retirement savings plan Defined Contribution Plan, Employer Discretionary Contribution Amount Changes in operating assets and liabilities: Increase (Decrease) in Operating Capital [Abstract] Abeona CLN1 Agreements Abeona C L N1 Agreements [Member] Abeona CLN1 agreements. 2025 Operating Leases, Future Minimum Payments, Due in Three Years Lease, Cost [Abstract] Cover [Abstract] Cash payment to acquire license agreement Payments To Acquire License Right Payments to acquire license right. Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense, Total Interest and penalties associated with income tax positions Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense Product and Service Product and Service [Domain] Other expense Other Nonoperating Expense 2027 Lessee, Operating Lease, Liability, to be Paid, Year Five Vested, Number of Shares Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Preferred Stock Tranche Liability Preferred Stock Tranche Liability Policy [Text Block] Preferred stock tranche liability. Current liabilities Liabilities, Current [Abstract] Fair value of shares transferred Fair Value Of Shares Transferred Fair value of shares transferred. Maximum Maximum [Member] Percentage of prepayment premium Percentage Of Prepayment Premium Percentage of prepayment premium UT Southwestern Agreement U T Southwestern Agreement [Member] UT southwestern agreement. Schedule of Total Remaining Stock-Based Compensation Expense for Stock Options, RSAs and RSUs (Detail) Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Underwriting discount and other offering costs Underwriting Discount and Other Offering Costs Underwriting discount and other offering costs. Net cash used in investing activities Net Cash Provided by (Used in) Investing Activities Furniture and Fixtures Furniture and Fixtures [Member] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Prepaid bonus Prepaid Bonus Prepaid bonus. Use of Estimates Use of Estimates, Policy [Policy Text Block] Debt instrument, basis spread on variable rate Debt Instrument, Basis Spread on Variable Rate Cash Equivalents, at Carrying Value, Total Cash equivalents Cash Equivalents, at Carrying Value Stock options were exercised during the period Stock Issued During Period, Value, Stock Options Exercised Finance Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration] Segments Segment Reporting, Policy [Policy Text Block] Property and equipment, useful life Property, Plant and Equipment, Useful Life On-site generation lease. On Site Generation Lease [Member] On Site Generation Lease Corporate alternative minimum tax on large corporations Effective Income Tax Rate Reconciliation, Tax Credit, Percent Effective Income Tax Rate Reconciliation, Tax Credit, Percent, Total Total principal payments Long-Term Debt, Gross Common stock, shares authorized Common stock, shares authorized Common Stock, Shares Authorized Trading Symbol Trading Symbol Right-of-use asset impairments Deferred Tax Assets Right-of-use Asset Impairment Deferred tax assets right-of-use asset impairment. Title of Individual Title of Individual [Domain] Subsequent Event Type Subsequent Event Type [Axis] Non-cash lease expense Operating Lease, Right-of-Use Asset, Amortization Expense Lease liabilities, current portion Lease Liability Current Lease liability current. Deferred Offering Costs Deferred Charges, Policy [Policy Text Block] Risk-free interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Accounts Payable, Current, Total Accounts payable Accounts Payable, Current Through December 31, 2021 Term Loan Through December Thirty One Twenty Twenty One [Member] Term loan through december thirty one twenty twenty one. Plan Name Plan Name [Axis] Title of Individual Title of Individual [Axis] Long-Lived Tangible Asset Long-Lived Tangible Asset [Domain] Common stock, par value per share Common Stock, Par or Stated Value Per Share Entity Well-known Seasoned Issuer Entity Well-known Seasoned Issuer Dallas Lease Dallas Lease [Member] Dallas lease. Variable lease cost Variable Lease, Cost License agreement regulatory related milestones maximum amount payable License Agreement Regulatory Related Milestones Maximum Amount Payable License agreement regulatory related milestones maximum amount payable. Comprehensive Loss Comprehensive Income, Policy [Policy Text Block] Share-based payment award, RSU/RSA granted Restricted units/stock granted, Number of Shares Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Finance Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration] Revenue performance obligation, expected period Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Period Weighted-average exercise price Share-based payment award, options granted, exercise price per share Options granted, Weighted Average Exercise Price Debt Instrument [Line Items] Debt Instrument [Line Items] Long-term Debt, Type Long-Term Debt, Type [Domain] Prepaid research and development Prepaid Research And Development Contracts Prepaid research and development contracts. Anti-dilutive securities excluded from computation of diluted net loss per share Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Supplemental disclosure of noncash investing and financing activities: Noncash Investing and Financing Items [Abstract]